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LASIX (FUROSEMIDE) TABLETS: PRESCRIBING INFORMATION

DESCRIPTION

Lasix is a diuretic which is an anthranilic acid derivative. Lasix tablets for oral administration contain furosemide as the active ingredient and the following inactive ingredients: lactose monohydrate NF, magnesium stearate NF, starch NF, talc USP, and colloidal silicon dioxide NF. Chemically, it is 4chloro-N-furfuryl-5-sulfamoylanthranilic acid. Lasix is available as white tablets for oral administration in dosage strengths of 20, 40 and 80 mg. Furosemide is a white to off-white odorless crystalline powder. It is practically insoluble in water, sparingly soluble in alcohol, freely soluble in dilute alkali solutions and insoluble in dilute acids.


CLINICAL PHARMACOLOGY

Lasix tablets clinical pharmacology


INDICATIONS AND USAGE

Edema

Lasix is indicated in adults and pediatric patients for the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and renal disease, including the nephrotic syndrome. Lasix is particularly useful when an agent with greater diuretic potential is desired.

Hypertension

Oral Lasix may be used in adults for the treatment of hypertension alone or in combination with other antihypertensive agents. Hypertensive patients who cannot be adequately controlled with thiazides will probably also not be adequately controlled with Lasix alone.


CONTRAINDICATIONS

Lasix is contraindicated in patients with anuria and in patients with a history of hypersensitivity to furosemide.


WARNINGS

Lasix tablets warnings


PRECAUTIONS

Lasix tablets precautions


DRUG INTERACTIONS

Lasix tablets drug interactions


NONCLINICAL TOXICOLOGY

Lasix tablets nonclinical toxicology


USE IN SPECIFIC POPULATIONS

Lasix tablets use in specific populations


ADVERSE REACTIONS

Lasix tablets adverse reactions


OVERDOSAGE

Lasix tablets overdosage


DOSAGE AND ADMINISTRATION

Lasix tablets dosage and administration


HOW SUPPLIED

Lasix (Furosemide) Tablets 20 mg are supplied as white, oval, monogrammed tablets in bottles of 100, 500, and 1000.
Lasix (Furosemide) Tablets 40 mg are supplied as white, round, monogrammed, scored tablets in bottles of 100, 500, 1000 and unit dose packs of 100.
Lasix (Furosemide) Tablets 80 mg are supplied as white, round, monogrammed, facetted edge tablets in bottles of 50 and 500.

Note: Dispense in well-closed, light-resistant containers. Exposure to light might cause a slight discoloration. Discolored tablets should not be dispensed.

Storage

Store at 25°C (77°F); excursions permitted to 15 - 30°C (59 - 86°F).

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